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United States of America

FCO - UK information on the United States
Updated: 25 July 2002

SUMMARY
Most visits to the United States are trouble-free. However, visitors should continue to be vigilant about their personal security.

SAFETY AND SECURITY<
R />Travellers to the United States should use common sense and take basic precautions.

If staying in a hotel, do not leave your door open at any time.

Do not wear ostentatious jewellery and avoid walking in obviously run down areas.
If arriving at night, take a taxi to your hotel and collect your hire car the next day.
If departing on an evening flight avoid leaving luggage and souvenirs in view in your hire car during the day. Thieves are targeting these vehicles and stealing the contents.
Drive on main highways and use well-lit car parks.

Do not stop if your car is bumped from behind. Instead, indicate to the other driver to follow you to the nearest public area and call for police assistance.
Do not sleep in your car on the roadside or in rest areas.
LOCAL LAWS AND CUSTOMS
Travellers wishing to visit Canada during their stay should contact the Canadian Consulate and US Immigration and Naturalisation Service for entry clearance requirements. If travellers have 90 day visa waiver for US, they should not wait until the end of their stay to travel between US and Canada. Travellers must not overstay past expiration date of their visa as they may risk being denied entry in either country or be deported. Travellers need to carry passports, round trip airline tickets showing their confirmed departure for return from US or Canada to country of origin, and they may need to show proof of sufficient funds to cover their stay.

Travellers should be aware that the age of consent varies from state to state in the US, as does the age at which someone may legally buy and consume alcohol.
ENTRY REQUIREMENTS
Foot and Mouth Disease:
Travellers are prohibited from carrying into the US any agricultural products, particularly animal products – including dairy products – that could spread FMD. (Some hard cheeses and canned meats are permitted. If you are in any doubt, you must check with a US customs or US Department of Agriculture (USDA) official immediately on arrival in the airport terminal). Passengers are required to tick the appropriate box on the US Customs declaration form if they have recently visited a zoo, or been on a farm or in contact with livestock. Passengers are specifically required to identify any farm contacts to US Customs and USDA officials. All luggage is subject to inspection. Penalties for not declaring farm visits or prohibited items can run to $1,000.

All US ports of entry and airports are on heightened alert to ensure that passengers, luggage and cargo are checked as appropriate. This includes placing additional inspectors and dog teams at airports to check incoming flights and passengers.

USDA are saying that soiled shoes, clothing or luggage will be disinfected on arrival. Food products and any other items suspected of potentially carrying the FMD virus will be confiscated and destroyed.
HEALTH
Medical treatment can be very expensive; there are no special arrangements for British visitors. The British Embassy and Consulates-General cannot assist with medical expenses.

Travellers who are HIV-positive
Travellers to the United States who are HIV-positive are not eligible, under current United States visa law, to travel visa free under the Visa Waiver Programme. They are required to apply for a visa and a waiver of the ineligibility before travelling. US immigration authorities state applicants’ details will remain confidential and an applicant’s HIV status will not/not be declared on their passport. For more details contact the US Embassy in London.
GENERAL
Comprehensive travel and medical insurance is essential.
NATURAL DISASTERS
Visitors to the United States will be aware of reports of large-scale wild and forest fires throughout the country. Those travelling to affected areas should be particularly vigilant and pay attention to advice from local authorities and press and radio announcements about personal safety and how to avoid starting fires. Further information can be obtained from the National Interagency Fire Centre, 3833 S. Development Avenue, Boise, Idaho, 83705-5354; tel: +1 208 387 5512; Website: www.nifc.gov

Travel News Headlines WORLD NEWS

Date: Thu 14 Nov 2019
From: Larry Lutwick <lutwick.larry@mayo.edu> [edited]

Over the past 5 days, our health care facility in northwest Wisconsin, USA, has seen 3 women hospitalized with _E coli_ O157 infection. All presented with significant abdominal pain without fever and watery diarrhoea which in 2 progressed to bloody diarrhoea. None of the 3 have manifested any evidence of haemolytic-uremic syndrome. Both of the women seen by the Infectious Diseases service stated that their diet contains a lot of salads.

We would appreciate any reports of upswings in the number of cases of this process in the upper Midwest USA or elsewhere.
--------------------------------------------
Larry Lutwick MD
Eau Claire, Wisconsin
=========================
[Although the classical source of enterohemorrhagic _E. coli_ infections is ground beef, fresh produce as in salad ingredients are also well represented as vehicles of transmission. ProMED would appreciate any further reports as the country health departments work on this as yet small outbreak. - ProMED Mod.LL]

[HealthMap/ProMED map available at:
Wisconsin, United States: <http://healthmap.org/promed/p/250>]
Date: Mon 4 Nov 2019
Source: WGME [edited]

Bath [Maine] police say they had another rabid fox attack Sunday [3 Nov 2019]. Police say around 11:45 am, they received a report in the area of 305 Washington Street that a fox had bit a 52-year-old man.

The man had been in his yard doing yardwork when he was attacked. He suffered bites and scratches on his legs.

Officers say they located the fox and killed it. The fox was confirmed to be rabid at the DHHS Health and Environmental Testing Lab in Augusta [Maine]. According to the lab, Bath has had 13 positive test results for rabies this year [2019].
======================
[In the USA, there exist several wildlife variants of _Lyssavirus_ that circulate in bats, raccoons, skunks, foxes and coyotes. Transmission rarely occurs between species, and these "spillover events" generally are not perpetuated in the recipient species.

While bats with rabies are found throughout the USA, main terrestrial reservoirs differ depending on the geographical location. Foxes are common carriers of rabies in New Mexico, Nevada and Alaska but not in Maine (see map here: <https://www.cdc.gov/rabies/exposure/animals/wildlife_reservoirs.html>). The main host for rabies in Maine is raccoons.

It is very important to make sure to keep the vaccination schemes of all domestic carnivores (i.e., dogs, cats, ferrets) in the area up to date and not to approach wildlife with unusual behavior. - ProMED Mod.PMB]

[HealthMap/ProMED-mail map:
Bath, Maine, United States: <http://healthmap.org/promed/p/26463>]
Date: Sun 3 Nov 2019
Source: The Citizen's Voice [edited]

A rare mosquito-transmitted virus that can be fatal to humans was recently confirmed in a deer found in Luzerne County. On [9 Oct 2019], the Pennsylvania Game Commission received a report of an emaciated deer standing on Swamp Road in Hunlock Township.

According to the agency, the deer -- a doe -- stood with its head down and didn't respond when humans approached. The animal was euthanized by Game Commission officials, and subsequent testing revealed it was infected with eastern equine encephalitis [EEE].

While there have been no reported cases of EEE in humans in the state, there have been several confirmations of the virus appearing in wildlife and livestock during October [2019].

In addition to the deer in Hunlock Twp, EEE has also been found in captive pheasants in Monroe County, horses in Carbon County, and 2 wild turkeys in Erie County.

Kevin Wenner, a biologist with the Game Commission in the Northeast Region Office, said the deer in Hunlock Twp represents the 1st instance of EEE in wildlife in the area, but it's difficult to predict if more cases will follow.

"We're not experiencing any significant mortality with deer and this happens to be one individual that was tested," he said. "It's possible that we're not aware of every case because a sick animal could die and never be found, but we're not getting an increase in calls regarding sick deer."

Equine encephalitis is transmitted to people, mammals, and birds through the bites of mosquitoes that have fed on infected birds. Most birds with EEE do not show any symptoms and never become ill. However, EEE can cause illness and death in some bird species -- most often pigeons, pheasants, turkeys and quail.

According to the Centers for Disease Control, symptoms of EEE in people develop 4 to 10 days after being bitten by an infected mosquito.

There are 2 types of illness that occur -- systemic and encephalitic. The former resembles flu-like symptoms and lasts up to 2 weeks. In the case of encephalitic illness (swelling of the brain), approximately a 3rd of all people afflicted die from the disease, according to the CDC. An average of 7 human cases of EEE are reported annually in the United States.

While the occurrence of EEE is not widespread in the region or state, Wenner said the threat will go away once cold weather arrives and knocks out the mosquito population.

"It sounds like this is a disease that comes and goes. It's not new, but we'll go through stretches where there are no cases for years and then it shows up," he said.

But right now, EEE is here, and since the disease has infected a deer in the wild, what does it mean for hunters? With archery deer season remaining open until [16 Nov 2019] and the statewide firearms season set to begin on [30 Nov 2019], are hunters at risk simply contacting a deer that harvest?

"There shouldn't be a fear that every deer out there has this and they shouldn't be consumed," Wenner said. "It's pretty uncommon in deer, and while people shouldn't be scared, they should be aware and take simple precautions to help prevent exposure."

Additionally, EEE can only be transmitted via a bite from an infected mosquito and not by direct contact, such as field dressing a deer. There is also no evidence that transmission can occur from consuming the meat of an infected animal, according to the Game Commission.

And even though birds are the primary host for the virus, Wenner said it doesn't mean that people should refrain from feeding birds. "Just take the necessary precautions to avoid being bitten by mosquitoes, such as using repellent and getting rid of any standing water around your home," he said.

Equine encephalitis is one of several diseases in Pennsylvania that can impact deer. Chronic wasting disease turned up in 2012 and has spread through parts of the south-central and south-western areas of the state, and epizootic hemorrhagic disease -- which is transmitted by biting flies -- has turned up in Pennsylvania in localized areas since 2002.

"It makes you think," said Game Warden Gerald Kapral, whose district includes Hunlock Twp. "Everyone sees a sick deer and they assume its chronic wasting disease, but this EEE case is an example that there's more out there."  [Byline: Tom Venesly]
===================
[Eastern equine encephalitis (EEE) virus (Togaviridae, _Alphavirus_) is maintained in an enzootic transmission cycle involving ornithophagic mosquitoes, specifically _Culiseta melanura_ (Diptera: Culicidae), and passerine birds in freshwater swamp foci. The virus is focally endemic in eastern North America, the Caribbean, and Central and South America.

Because there are very few reports of disease due to EEEV in deer, coupled with a relatively high antibody prevalence at endemic sites, we believe that deer are commonly infected with this virus but are relatively refractory to clinical disease. EEE, therefore, may not be an important disease in white-tailed deer in the eastern United States. - ProMED Mod.PMB]

[HealthMap/ProMED-mail map of Pennsylvania, United States:
Pennsylvania county map:
Date: Sun 3 Nov 2019
Source: The North Platte Telegraph [edited]

The Southwest Nebraska Public Health Department has confirmed a case of [a] hantavirus [infection] in the 9-county [Chase, Dundy, Frontier, Furnas, Hayes, Hitchcock, Keith, Perkins, and Red Willow] health district. This is the 1st reported case of hantavirus in the southwest Nebraska area in over 6 years.

According to the Centers for Disease Control and Prevention, hantavirus infection is usually found in rural areas where forest, fields, and farms offer suitable habitat for rodents. Hantavirus in the US is spread to people from rodents like mice, most commonly when fresh rodent urine, droppings, or nesting materials are stirred up. Tiny droplets containing the virus get into the air and are then breathed in.

"This can easily happen when cleaning out grain bins, barns or old abandoned buildings," said Melissa Propp, RN.

Symptoms of hantavirus usually start out with vague flu-like symptoms approximately several days to 6 weeks after exposure. A fever for 3-5 days, headache, muscle aches, chills, non-productive cough, nausea, vomiting or other gastrointestinal symptoms like diarrhea or abdominal pain are common. Tiredness and lightheadedness may also be present. Most people recover fully but some cases of hantavirus may be severe or even fatal. "If you have flu-like symptoms and have cleaned out a building with evidence of rodents, alert your provider," states Propp.  It is important not to stir up dust by sweeping or vacuuming.
Hantavirus [infections] can be prevented by following these tips:
- air out the building for a least 30 minutes prior to starting your cleaning. Open doors and windows to allow good air flow and leave the area while airing out;
- wear gloves while cleaning up urine and droppings. A dust mask may also be worn as additional protection;
- dampen the urine, droppings, and nesting materials with a mixture of 1-part bleach to 10 parts water or use a disinfectant. Allow to soak for 5 minutes prior to removal;
- clean counters, cupboards and other surfaces with disposable towels;
- mop floors rather than sweeping or vacuuming;
- for dirt floors wet the area down with bleach solution or disinfectant before removal of debris to keep down the dust;
- disinfect any tools used in the cleaning process with a bleach solution.
- wash hands thoroughly with soap and water after cleaning tools and disposing of materials.

For more information about hantavirus visit
====================
[This is not the 1st case of a hantavirus infection in Nebraska. In May 2005, a western Nebraska man in his early 50s died after being infected with hantavirus. A 37-year-old rural Grant man became the state's 4th person to test positive for the potentially deadly hantavirus on 31 Aug 2002. A 30-year-old male of Lyman became the 1st person in 2002 to die from the disease in Nebraska on 13 Jun 2002. Other Nebraska cases include those of a 41-year-old male, of Champion, who was hospitalized in Kearney from 24 Jun 2002 to 14 Jul 2002 and another male, age not specified, of Benkleman, was diagnosed with the 1st known case of hantavirus in Nebraska in 1998. Both recovered. As of January 2017, Nebraska has reported 9 cases of hantavirus infection (<https://www.cdc.gov/hantavirus/surveillance/reporting-state.html>)

Although not mentioned, the hantavirus involved in these and the above case is likely Sin Nombre virus and its rodent host is the deer mouse (_Peromyscus manipulates_). Nebraska is within the geographic range of this rodent. Individuals in Nebraska and elsewhere within the range of this rodent are well advised to follow the recommendations listed above to avoid exposure to this virus.

An image of a deer mouse (_Peromyscus maniculatus_) can be accessed at

[HealthMap/ProMED-mail map of Nebraska, United States:
Nebraska county map:
Date: Tue 29 Oct 2019
Source: The Narragansett Times [edited]

The Rhode Island Department of Health (RIDOH) [has] confirmed [that] 2 individuals have been treated for exposure to the rabies virus since September [2019] after encounters with rabid wild animals in Narragansett [Washington County]. The department also noted [that] 4 wild animals from Narragansett have tested positive for the potentially deadly virus since March [2019].

Four animals submitted for testing at RIDOH's State Health Laboratories have tested positive for rabies this year [2019]. The 1st came in March -- a rabid skunk on Tarzwell Drive. In August, a raccoon spotted on Kathy Street tested positive for the virus. Then, in September, a woodchuck/groundhog seen on Onondega Road was confirmed
to possess the virus. Most recently, this month [October 2019], a skunk on Wild Field Farm Road tested positive for rabies after an encounter with a dog in the yard of a residence on the street.

"We received confirmation of another skunk captured on [Fri 18 Oct 2019] after attacking a dog, tested positive for rabies," wrote Narragansett Animal Control on its Facebook page on 21 Oct 2019.

Residents have become concerned regarding the prevalence of the virus locally, though RIDOH stated the increase in confirmed cases of the virus was not cause for alarm. "The number of rabid animals identified in any given community varies from year to year," said Joseph Wendelken, RIDOH public information officer. "The number of rabies-positive animals [confirmed in Narragansett] in 2019 has been higher than expected, but we're dealing with relatively small numbers. The increase in 2019 is not considered statistically significant, meaning the increase is likely due to chance. For example, we have seen year-to-year increases like this in other communities in the past."

According to RIDOH, 5 wild animals from Narragansett were tested by the department in 2016; 4 in 2017, and 9 in 2018. All of these tests were negative. In 2019, 7 animals have so far been tested by RIDOH. 4 have tested positive. According to Monica Tutko, who works full time as a Narragansett animal control officer, the animal control department has received over 50 calls for animals "appearing to be sickly in some manner" since June of last year [2018]. The animal control officer also stated in July of this year, a fox believed to be possibly rabid attacked multiple people and animals in a 24-hour period and was never caught for testing, despite efforts to do so.

Tutko said the situation in Narragansett needed to be taken "quite seriously." RIDOH said while the increase did not indicate a concerning trend upward, residents should still take precautions to decrease risk of exposure. "You can't tell if an animal has rabies by just looking at it," said Wendelken when asked how rabid animals could be identified. "The only way doctors can know for sure if an animal or a person has rabies is to do laboratory tests. A clue though is if the animal is acting strangely. Some animals may act mad when they have rabies. They will be hostile and may try to bite people or other animals. Other animals may act timid or shy when they have rabies. A wild animal might move slowly or act tame. The best thing to do is to never feed or approach a wild animal. Be careful of pets you do not know."

One resident posted to a private resident Facebook page about a September [2019] encounter he had with a rabid woodchuck leaving both he and his wife in need of multiple shots after a recommendation for treatment from RIDOH. The resident concluded the post by asking what was being done to combat the rise in local rabid wild animals.

If a human is bitten by an animal believed to be possibly rabid, washing the wounded area with soap and water for 10-15 minutes is recommended by RIDOH to help remove the virus. The department also strongly suggests contacting a doctor or hospital ER immediately and alerting the local animal control officer of the incident in an effort to further protect others from potential exposure. The public can also call the Rhode Island Department of Health Rabies Control Program to report an exposure (401-222-2577 Monday-Friday from 8:30 am to 4:30 pm; 401-276-8046 after hours). If the animal is a stranger's pet, ask for the owner's contact information, according to RIDOH.

The department also had recommendations when it comes to pet safety. "If your pet has been bitten, try to find out what animal attacked your pet," said Wendelken. "Do not touch the attacking animal. Wear rubber gloves and use a hose to wash your pet's wounds. Do not touch your pet with bare hands. There may be saliva from the attacking animal on your pet. Call your pet's vet immediately, even if the wound is minor. Local animal control should be contacted to report the incident."

RIDOH stated even if a pet has already been recently vaccinated for the virus, a veterinarian should still be contacted immediately and the incident should still be reported to the local animal control. Further recommendations include never approaching a wild animal, being careful around pets one is not familiar with, refraining from petting stray cats or dogs and contacting local animal control if any animal is observed acting strangely.

In the United States, animals most likely to carry rabies are wild animals such as bats, raccoons, skunks, foxes, and woodchucks. Dogs, cats, and ferrets can also carry rabies, but they are less likely to be infected because of the high vaccination rates among pets.

"Rabies is a fatal but preventable viral disease," concluded Wendelken. "The virus infects the central nervous system. If a person does not receive the appropriate medical care after a potential rabies exposure, the virus can cause disease in the brain, ultimately resulting in death. However, rabies can be prevented by vaccinating pets, staying away from wildlife, and seeking medical care after potential exposures before symptoms start."

Due to the recent exposures, the Narragansett Animal Control is stepping up its number of posts concerning the virus on social media and is hosting a public rabies vaccination clinic for pets at the Narragansett Community Center on Sat 9 Nov 2019 from 10 am to 12 pm. USD 10 cash only and attendees are asked to bring previous pet vaccination records if available. The general public is invited and attendance is not restricted based on Narragansett residence.

Rabies is considered a rare disease in the United States with fewer than 1000 confirmed cases per year.  [byline: Philip Cozzolino]
=====================
[HealthMap/ProMED-mail map of Rhode Island, United States:
 county map:

It is very sad that the person in North Carolina had to have his dog euthanized. But it could have been avoided if he had gotten his pet vaccinated. Let's all learn the lesson here and get our pets vaccinated, and keep those vaccinations up to date. Protecting your pet against this fatal disease applies to all pets, including dogs, cats, horses, cattle, sheep, and goats.

Often it is a skunk or raccoon wandering through a pasture who nips the horse or cow on the nose, thus transmitting this virus. Any animal with rabies can be frightening but a large animal of many pounds more than most of us is exceedingly unsettling. Please vaccinate your pets.

The Rhode Island article is the only article in this group doing community wide low-cost rabies vaccinations for pets. I wonder how many horses or goats or other animals will be brought for a rabies vaccination. Reporting a bite is important, but especially if it is a wild animal or an animal you are unfamiliar with. Remember your life is worth more than guessing if an animal has been vaccinated. - ProMED Mod.TG]
More ...

World Travel News Headlines

Date: Sun 3 Nov 2019
Source: Nigeria Centre for Disease Control (NCDC) [edited]

Highlights
- In the reporting week 44 (28 Oct - 3 Nov 2019), 11 new confirmed** cases were reported from Ondo (6) and Edo (5) states with one new death from Edo state.
- From 1 Jan - 3 Nov 2019, a total of 4396 suspected* cases have been reported from 23 states. Of these, 754 were confirmed positive, 19 were probable, and 3623 were negative (not a case).
- Since the onset of the 2019 outbreak, there have been 158 deaths in confirmed cases. Case-fatality ratio in confirmed cases is 21%.
- A total of 23 states (Edo, Ondo, Bauchi, Nasarawa, Ebonyi, Plateau, Taraba, Adamawa, Gombe, Kaduna, Kwara, Benue, Rivers, Kogi, Enugu, Imo, Delta, Oyo, Kebbi, Cross River, Zamfara, Lagos, and Abia) have recorded at least one confirmed case across 86 local government areas [LGAs] - Figure 1.
- 93% of all confirmed cases are from Edo (38%), Ondo (31%), Ebonyi (7%), Bauchi (7%), Taraba (5%), and Plateau (5%) states - Figure 1.
- Predominant age group affected is 21-40 years (range: greater than one month to 98 years; median age: 34 years) - Figure 6.
- The male-to-female ratio for confirmed cases is 1:1 - Figure 6.
- In the reporting week 44, no new healthcare worker was affected. A total of 19 healthcare workers have been infected since the onset of the outbreak in 10 states: Edo (6), Ondo (4), Ebonyi (2), Enugu (1), Rivers (1), Bauchi (1), Benue (1), Delta (1), Plateau (1) and Kebbi (1) with 2 deaths in Enugu and Edo states.
- Nine patients are currently being managed at various treatment centres across the country: Irrua Specialist Teaching Hospital (ISTH) treatment Centre (7) and Federal Medical Centre, Owo (2).
- A total of 8400 contacts have been identified from 21 states. Of these, 356 (4.2%) are currently being followed up, 7967 (94.8%) have completed 21 days follow-up, while 12 (0.1%) were lost to follow-up. A total of 132 symptomatic contacts have been identified, of which 65 (49.2%) have tested positive.
- National Lassa fever multi-partner, multi-sectoral Technical Working Group (TWG) continues to coordinate response activities at all levels.

Figures [available at the source URL above]
-------------------------------------------
Figure 1 [map]. Randomised distribution of confirmed Lassa fever cases in Nigeria as at 3 Nov 2019.
Figure 2 [map]. LGAs with confirmed Lassa fever cases in Nigeria as at 3 Nov 2019.
Figure 3 [graph]. Epicurve of Lassa fever confirmed cases (754) in Nigeria - week 01-44, 2019.
Figure 4 [graph]. November 2019. Weekly trends of Lassa fever confirmed cases in Nigeria, 2016/week 01-2019/week 44.
Figure 5 [graph]. Confirmed Lassa fever cases in Nigeria with state-specific case-fatality rates (CFR) as at 3 Nov 2019.
Figure 6 [graph]. Age-sex distribution of confirmed Lassa fever cases in Nigeria as at 3 Nov 2019.

*Suspected case describes any individual presenting with one or more of the following: malaise, fever, headache, sore throat, cough, nausea, vomiting, diarrhoea, myalgia, chest pain, hearing loss, and either (a) history of contact with excreta or urine of rodents or (b) history of contact with a probably or confirmed Lassa fever case within a period of 21 days of onset of symptoms, or any person with inexplicable bleeding/hemorrhagia.
**Any suspected case with laboratory confirmation (positive IgM antibody, PCR, or virus isolation)
==================
[The 11 new confirmed and 4396 suspected cases indicate that Lassa fever (LF) virus transmission is continuing. Nigeria should be in the period of the year when fewer cases usually occur, as illustrated in the graph in Figure 3 (at the source URL above), but more cases are still occurring. There has been a peak in case numbers between weeks 1 and 11 (January-March) over the past 3 years and probably will be the case again next year (2020).

The number of confirmed deaths has increased by 2 to 158. Fortunately, there are no new healthcare workers infected during this reporting period, and the total number of infected healthcare workers remains at 19, a likely indication that effective barrier nursing and the use of personal protective equipment are being employed. This outbreak remains widespread so far in 2019, with confirmed cases occurring in 23 states, and the number of affected LGAs remains at 86. ProMED-mail readers may wish to see the maps and graphs (Figures 1-6) that are available at the source URL above.

Transmission of LF virus occurs when individuals are in contact with rodent reservoir host excreta or are within healthcare facilities. It would be interesting to know whether the prevalence of Lassa fever virus has been increasing in populations of rodent hosts in areas where human cases are occurring.

Images of the rodent reservoirs of Lassa fever virus:
_Mastomys natalensis_:
_Mastomys erythroleucus_ and _Hylomyscus pamfi_:

There is no mention in the plans above of public education for avoidance of contact with these rodents and their excreta. - ProMED Mod.TY]

[Maps of Nigeria:
Date: Thu 14 Nov 2019
From: Larry Lutwick <lutwick.larry@mayo.edu> [edited]

Over the past 5 days, our health care facility in northwest Wisconsin, USA, has seen 3 women hospitalized with _E coli_ O157 infection. All presented with significant abdominal pain without fever and watery diarrhoea which in 2 progressed to bloody diarrhoea. None of the 3 have manifested any evidence of haemolytic-uremic syndrome. Both of the women seen by the Infectious Diseases service stated that their diet contains a lot of salads.

We would appreciate any reports of upswings in the number of cases of this process in the upper Midwest USA or elsewhere.
--------------------------------------------
Larry Lutwick MD
Eau Claire, Wisconsin
=========================
[Although the classical source of enterohemorrhagic _E. coli_ infections is ground beef, fresh produce as in salad ingredients are also well represented as vehicles of transmission. ProMED would appreciate any further reports as the country health departments work on this as yet small outbreak. - ProMED Mod.LL]

[HealthMap/ProMED map available at:
Wisconsin, United States: <http://healthmap.org/promed/p/250>]
Date: Tue 12 Nov 2019
Source: Daily Times [edited]

[_Naegleria fowleri_] has claimed another life in Karachi on [Mon 11 Nov 2019]. This was the 16th death reported in the ongoing year [2019] because of the disease. According to details, a 28-year-old resident of New Karachi area was brought to a private clinic 4 days ago where he died of the disease during treatment.

According to the researchers, _Naegleria_ has a fatality rate of more than 98%. Infections can happen when contaminated water enters the body through the nose. It cannot be passed person-to-person.

The amoeba travels from the nasal membranes to the brain. Symptoms are initially very mild, including a headache, stiff neck, fever, and stomach pain. Death usually occurs 5 to 7 days after infection.

_N. fowleri_ is a microscopic amoeba, which is a single-celled living organism. It can cause a rare and devastating infection of the brain called primary amoebic meningoencephalitis (PAM). The amoeba is commonly found in warm freshwater such as lakes, rivers, ponds, and canals.

Once the amoeba enters the nose, it travels to the brain where it causes PAM (which destroys brain tissue) and is usually fatal. Infections usually occur when it is hot for prolonged periods of time, which results in higher water temperatures and lower water levels.
====================
[Even though the weather has cooled considerably in northern parts of the country, Sindh province, which includes Karachi, continues to experience hot and humid climate which is conducive to the proliferation of the Naegleria parasite.

A public awareness message from the Government of Sindh Health Department can be seen at

Optimum chlorination is the key measure to prevent _Naegleria fowleri_ infection. In the absence of chlorination of the supply water in the city, residents need to clean water tanks and chlorinate water in the tanks. - ProMED Mod.UBA]

[HealthMap/ProMED map available at:
Date: Tue 12 Nov 2019
Source: Outbreak News Today [edited]

Moncton is a city of some 85,000 people in south-eastern New Brunswick, Canada. In a CBC [Canadian Broadcasting Corporation) report today [12 Nov 2019], it is reported that a 3rd Creutzfeldt-Jakob disease (CJD) case this year [2019] -- all 3 cases had cataract surgery at the Moncton Hospital.  In April [2019], Moncton Hospital reported the identification 2 separate cases where a patient with probable Creutzfeldt-Jakob disease (CJD) had cataract surgery in the facility.

Dr Gordon Dow, division head of infectious diseases at the Moncton Hospital, said even he was shocked when another case of CJD was discovered.  "I think even though there's the overwhelming weight of evidence suggesting that we've had a cluster of sporadic cases, there is no need for public alarm," Dow said. "This is not an indication that there's been an outbreak of CJD."

Prion diseases are rare, fatal, degenerative brain disorders that are thought to occur worldwide in both humans and animals. They belong to the general category of brain diseases called proteinopathies, which also includes Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). Although there are several forms of human prion disease, the most common is Creutzfeldt-Jakob disease (CJD).  Since January 1998, Canada has reported 1037 definitive and probable CJD cases and New Brunswick has seen 31 cases during this period.
Date: Mon 11 Nov 2019
Source: Pan American Health Organization (PAHO)

Mexico has become the 1st country in the world to receive validation from the World Health Organization (WHO) for eliminating dog-transmitted rabies as a public health problem. "Eliminating [dog-transmitted] rabies doesn't happen by accident," said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. "It takes political resolve, careful planning, and meticulous execution. I congratulate the Government of Mexico on this wonderful achievement and hope many other countries will follow its example."

Rabies causes 60,000 deaths each year, mainly in Asia and Africa. In Latin America and the Caribbean, new cases of rabies were reduced by more than 95 percent in humans and 98 percent in dogs since 1983.

"By eliminating human rabies transmitted by dogs, Mexico is showing the world that ending infectious diseases for the next generation is possible and is the right way forward," said PAHO Director, Carissa F Etienne.

Mexico's achievement
--------------------
In order to achieve elimination, the country has implemented a national strategy for the control and elimination of rabies. This includes free, mass vaccination campaigns for dogs, that have taken place since the 1990's with more than 80 percent coverage; continuous and effective surveillance; public awareness-raising campaigns; timely diagnosis; and the availability of post-exposure prophylaxis in the country's public health services.

As a result, the country went from registering 60 cases of human rabies transmitted by dogs in 1990, to 3 cases in 1999, and zero cases in 2006. The last 2 cases occurred in 2 people from the State of Mexico, who were attacked in 2005 and presented symptoms in 2006.

The validation process
----------------------
WHO considers a country to be free of rabies after registering 2 years of zero transmission of rabies to humans. However, there was previously no process to verify the achievement of this goal, until this was developed by PAHO/WHO. Mexico became the 1st country in the world to begin this in December 2016.

The validation process was extensive and included the creation of a group of independent international experts established by PAHO/WHO. It also included the preparation, by Mexico, of an almost 300-page file containing all historical information about the situation of rabies in the country. PAHO and its specialized center in veterinary public health, PANAFTOSA, accompanied and supervised the implementation of the validation process throughout.

The group of experts carried out a mission to Mexico in September 2018 to review the file and verify the country complied with all WHO requirements. In September 2019, the group recommended the Director General of WHO and PAHO validate the elimination.

Moving forward
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In order to sustain elimination, PAHO/WHO recommends continuing all rabies prevention, surveillance and control actions, particularly as rabies virus continues to circulate among wild animals such as bats.

PAHO collaborated with the countries of the Americas to eliminate rabies through technical cooperation, staff training, periodic meetings between those responsible for the issue in-country, and through the provision of recommendations on international standards. As of September 2019, there have been zero cases of rabies transmitted by dogs in humans in the Americas.

In addition to rabies, Mexico eliminated onchocerciasis in 2015 and trachoma in 2017, 3 of the more than 30 infectious diseases and related conditions that PAHO's new Communicable Disease Elimination Initiative in the Region of the Americas has set as a goal for elimination from the continent by 2030.
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[This is certainly an outstanding achievement and should be celebrated by all. It is also an example to other countries.  Of course, someone acquiring rabies from a bat would be outside of this situation. This WHO/PAHO validation specifically refers to rabies acquired from dog bites. This is a great milestone. Congratulations Mexico! - ProMED Mod.TG]

[HealthMap/ProMED-mail map of Mexico:
Date: Mon, 18 Nov 2019 08:37:15 +0100 (MET)

Jakarta, Nov 18, 2019 (AFP) - An endangered Sumatran Tiger has mauled to death an Indonesian farmer and seriously injured a domestic tourist, a conservation official said Monday.   The fatal attack happened Sunday at the farmer's coffee plantation on Sumatra island where the 57-year-old wrestled with the big cat before it killed him, according to Genman Hasibuan, head of the South Sumatra conservation agency.   "The farmer was attacked while he was cutting a tree at his plantation," he told AFP on Monday.   The mauling came a day after the same tiger attacked a group of Indonesian tourists who were camping at a local tea plantation in South Sumatra's Mount Dempo region.

One of the tourists was rushed to hospital for wounds to his back after the cat stormed into his tent, Hasibuan said.   The animal, which remains loose in the protected-forest area, is believed to be one of just 15 critically endangered tigers in South Sumatra, which has seen five tiger attacks this year, including two fatal incidents, Hasibuan said.

Human-animal conflicts are common in the vast Southeast Asian archipelago, especially in areas where the clearing of rainforest to make way for palm oil plantations is destroying animals' habitats and bringing them into closer contact with people.   In March last year, a man was killed by a tiger in Sumatra's Riau province while several months earlier a tiger also killed a plantation worker in the area.   Sumatran tigers are considered critically endangered by protection group the International Union for Conservation of Nature, with 400 to 500 remaining in the wild.
Date: Fri, 15 Nov 2019 17:12:24 +0100 (MET)

Karachi, Nov 15, 2019 (AFP) - Pakistan has become the first country in the world to introduce a new typhoid vaccine, officials said Friday, as the country grapples with an ongoing outbreak of a drug-resistant strain of the potentially fatal disease.   The vaccine, approved by the World Health Organization (WHO), will be used during a two-week immunisation campaign in southern Sindh province.

Sindh is where most of Pakistan's 10,000 cases of typhoid have been documented since 2017.    "The two-week campaign beginning from today would target over 10 million children of nine months to 15 years of age," Azra Pechuho, the health minister in Sindh province, said in Karachi on Friday.   The new vaccines have been provided by Gavi, the Vaccine Alliance, to the Pakistani government free of cost.

After the two-week campaign, it will be introduced into routine immunisations in Sindh, and in other areas of Pakistan in the coming years.   Pakistan spends a meagre amount of its national resources on public health and a majority of its population remains vulnerable to contagious diseases such as typhoid.   In 2017, 63 percent of the typhoid cases documented and 70 percent of the fatalities were children, according to a joint press release from the Pakistani government, WHO and Gavi.
Date: Sat, 16 Nov 2019 05:50:25 +0100 (MET)
By Abhaya SRIVASTAVA

New Delhi, Nov 16, 2019 (AFP) - A thick grey smog choked New Delhi for the fifth day Saturday, adding to a mounting pollution health crisis, but retired naval commander Anil Charan is one of the vast majority of the city's 20 million inhabitants who do not wear a mask.   Indian media is packed with warnings about the risk of premature death, lung cancer and particular danger to children from PM2.5 -- tiny particles that get into the bloodstream and vital organs -- carried in the smog.   But the smartly-dressed Charan was among shoppers in Delhi's upmarket Khan Market district browsing the luxury clothes and jewellery stores without a mask, seemingly oblivious to the risk.   Many are too poor to afford protection but others simply do not like the way a pollution mask looks.

Charan, wearing aviator sunglasses, said it did not fit his "rough and tough" image.   "I have been brought up in this kind of atmosphere, the smog and all, so I am kind of used to it. And being a naval officer I think if I wear a mask I will think I am a sissy," he said.   Doctors say face masks must be worn and air purifiers used at home and in offices.   There are a variety of masks to choose from. A basic cloth version can cost as little as 50 rupees (70 US cents) but the protection they offer is debatable.    More reputable types start from 2,500 rupees ($34) while some Khan Market stores charge more than 5,500 rupees ($75) for top of the range imported models.

- Bare-faced bravado -
The mask-look worried a lot of the Khan Market shoppers and diners however. Some said the danger had been overblown.   "I know I am risking my health but I am not very comfortable wearing them (masks)," said Ritancia Cardoz, who works for a private company.   "I don't find it appealing," she told AFP.   Lopa Diwan, on a visit to the capital from the provinces, said the Delhi air was "not as bad as it is being made out to be."   "So many people advised me not to go to Delhi because of the pollution but I don't think it's that bad. I don't see people dying," she said.

Pollution -- blamed on industrial and car emissions mixed with stubble fires on thousands of farms surrounding the city -- has been building up each winter for the past decade. The past five years have been particularly bad.   The toxic air cuts short the lives of one million people in India every year, according to government research published earlier this year.    Concentrations of the most harmful airborne pollutants in Delhi are regularly about 20 times the World Health Organisation safe limit. That rams home the city's reputation as the world's most polluted capital.   Some foreign companies and embassies now do not let families move to Delhi, or at least give strong warnings about the pollution.

The Delhi government has given out hundreds of thousands of masks to children and closed schools for four of the past five days. Construction is banned and cars can only go on the roads on alternate days.   But still only a tiny number of inhabitants follow medical advice when outside. Rickshaw drivers who earn about $7 a day on an average say they cannot afford masks.   Chand Babu, a car park attendant at Khan Market, said he could buy one of the cheaper masks but it was too much of a hassle to wear.   "I have to blow the whistle all the time so it's inconvenient."   Babu does worry, however, about his three children who also do not have masks. "They go outside to play. The problem is real, but what do we do, tell me?"
Date: Sun, 17 Nov 2019 14:28:44 +0100 (MET)
By Filippo MONTEFORTE with Charles ONIANS in Rome

Venice, Nov 17, 2019 (AFP) - Venice's St Mark's Square was closed on Sunday as the historic city suffered its  third major flooding in less than a week, while rain lashing the rest of Italy prompted warnings in Florence and Pisa.   Venice's latest "acqua alta", or high water, hit 150 centimetres (just under five feet) on Sunday, lower than Tuesday's 187 centimetres -- the highest level in half a century -- but still dangerous.   "The water has stopped rising," tweeted mayor Luigi Brugnaro, who has estimated damage so far from the invading salt water at over one billion euros (dollars).   "High of 150 centimetres... Venice is working to restart," Brugnaro said after the sea water swamped the already devastated city where authorities have declared a state of emergency.   To the south, Tuscany president Enrico Rossi tweeted a warning of a "flood wave" on the Arno and said boards were being installed on the swollen river's banks in Pisa "as a precautionary measure".

The Italian army tweeted photos of paratroopers helping to bolster river defences in Pisa, with authorities monitoring the same river in Florence after heavy rain made it rise dramatically overnight.   Arno flooding devastated Renaissance jewel Florence in 1966, killing around 100 people and destroying thousands of priceless works of art. Civil protection units in Florence advised citizens "not to stand near the Arno's riverbanks".   Firefighters tweeted footage of a hovercraft being deployed to rescue stranded citizens in southern Tuscany's Grossetano province.

- Brief respite -
The renewed threat from exceptionally high tides in Venice came after a brief respite on Saturday.   Emergency workers removed temporary walkways from St Mark's Square as the water started to rise on Sunday, with only police and soldiers visible at around midday.   The top tourist site had already been shut for several hours on Friday as strong storms and winds battered the region, leaving it submerged by sea surges.

Churches, shops and homes have also been inundated in the Renaissance city, a UNESCO World Heritage site.   A massive infrastructure project called MOSE has been under way since 2003 to protect the city, but the multi-billion euro project has been plagued by cost overruns, corruption scandals and delays.   "We weren't expecting the high waters to be so exceptionally high," said Guido Fulgenzi, who had planned to open his cafe on St Mark's square this week.   "We're paying the price" for the MOSE project not being completed, he said, sloshing around in his flooded kitchen and pointing to Tuesday's high water mark on the wall.   The crisis has prompted the government to release 20 million euros ($22 million) in funds to tackle the devastation.   Culture Minister Dario Franceschini has warned that the task of repairing the city, where more than 50 churches have suffered damage, will be huge.

- Hotel reservations cancelled -
Residents whose houses have been hit are eligible for up to 5,000 euros in immediate government aid, while restaurant and shop owners can receive up to 20,000 euros and apply for more later.   Most of the city's cash machines were no longer working, making life even more difficult for tourists and Venetians.   "We didn't expect there to be so much water, now we're soaked," said French tourist Magali Mariolou, visiting Venice for her wedding anniversary.   "We'll come back another year when it's a bit drier. The boots are heavy, they're full of water!"

Older residents who remember the infamous "acqua alta" of 1966, when the water rose to 1.94 metres, say they have not seen such frequent flooding before.   Hotels reported cancelled reservations, some as far ahead as December, following the widespread diffusion of images of Venice underwater.   Tuesday's high waters submerged around 80 percent of the city, officials said.   Many, including Venice's mayor, have blamed the disaster on global warming and warned that the country prone to natural disasters must wake up to the risks posed by ever more volatile seasons.   The Serenissima, as the floating city is called, is home to 50,000 residents but receives 36 million visitors each year.
Date: Mon, 18 Nov 2019 06:41:11 +0100 (MET)

Wellington, Nov 18, 2019 (AFP) - Samoa finalised plans for a compulsory measles vaccination programme Monday, after declaring a state of emergency as a deadly epidemic sweeps the Pacific nation.   At least six fatalities, including five children, have been linked to the outbreak of the virus, which has also hit other island states such as Tonga and Fiji.   Samoa is the worst affected with more than 700 cases reported from across all areas of the country, prompting the government on Friday to invoke emergency powers.

Declaring a state of emergency, the government said plans for compulsory measles, mumps and rubella (MMR) immunisations would be published on Monday.   "MMR vaccinations for members of the public who have not yet received a vaccination injection is now a mandatory legal requirement for all of Samoa," it said.   A national emergency operations centre to coordinate the measles response in the nation of 200,000 people was opened on Monday, with children aged six months to 19 years and non-pregnant females aged 20-35 given priority.

However, no information was immediately available on how the vaccinations would be administered or whether those who were not immunised would face sanctions.   Children are the most vulnerable to measles, which typically causes a rash and fever but can also lead to brain damage and death.   Samoa has closed all schools, kindergartens and the country's only university in a bid to halt the spread of the virus.   New Zealand, which is experiencing its own measles outbreak in the Auckland region, will this week send 30 nurses, 10 doctors and 3,000 MMR doses to Samoa.

University of Auckland immunologist Helen Petousis-Harris said even though measles was already widespread, the mass rollout of vaccinations could help limit the number of cases and reduce the death count.   She said it was also important to boost Samoa's low levels of immunisation and help prevent future outbreaks.   "In Samoa, the proportion of people who are immune to measles is very, very low, one of the lowest in the world," she told AFP.   "So if they aren't able to improve that, this is going to happen again."   The country's vaccination programme was briefly suspended last year when two babies died shortly after being given the MMR vaccine.   Subsequent investigations found the problem was not the widely used vaccine but the fact that nurses had prepared it incorrectly.

Neighbouring Tonga last week announced government primary schools and kindergartens would be closed until later this month as the number of measles cases in the kingdom approaches 200.   Fiji has reported four cases but says they are contained to a township west of the capital Suva.