Date: Wed, 1 May 2019 01:24:23 +0200

Buenos Aires, April 30, 2019 (AFP) - Tens of thousands of Argentines demonstrated Tuesday in a partial strike that grounded airplanes and shut banks and other businesses to protest the economic policies of President Mauricio Macri.   "I came here to protest because I can't manage on my salary. The government has to go. It hasn't managed to sort out the economic situation," said Juan Arrique, a 32-year-old trucker demonstrating in Buenos Aires.

The truck drivers' union was one of the main groups calling for the protests that saw airplanes parked on the tarmac and transit buses lined up in rows at their terminal.   Sea traffic was also suspended, most schools closed and many shops as well as banks were shut.   Macri's popularity has fallen in recent months, a disappointing sign for the president just six months out from elections in which he hopes to win a second term.   In an effort to reduce the state deficit, the government last year launched an austerity plan that has cut services to low-income Argentines.

The measures came in exchange for a $56 billion loan from the International Monetary Fund to help the South American country battle its currency crisis and soaring prices.   Inflation over the last 12 months was around 55 percent, while the spending power of ordinary citizens has been in freefall.   "Take Macri, leave the dollars," read one banner in reference to the IMF loan repayments.   The same slogan was also scrawled on the wall of a building next to that of the US bank JP Morgan.

Unemployment is increasing, poverty now affects 32 percent of the population and 41 percent of children, while businesses lay off workers and consumption drops.   The partial strike followed a protest called by trade unions in early April which saw thousands of demonstrators march in Buenos Aires against Macri's economic policies.
Date: Tue 9 Apr 2019
Source: El Tribuno [in Spanish trans. ProMED Mod. TY, edited]
<https://www.eltribuno.com/jujuy/nota/2019-4-9-1-0-0-se-registraron-11-casos-de-hantavirus-en-la-provincia>

Authorities of the Jujuy Ministry of Health yesterday [8 Apr 2019] confirmed that 11 cases of hantavirus [infections] are confirmed in the province, distributed in the localities of San Pedro, Palma Sola, Libertador General San Martin, and Calilegua.  "The majority of the affected people have a history of having gone fishing or hunting in the forest," and so "probably did not take the necessary precautions", stated the Jujuy Subsecretary of Prevention for Health, Veronica Serra.

The official stated that 11 hantavirus [infection] cases have been confirmed so far this year [2019], "all of them in the Jujuy Ramal [area]' she said.

Concerning the medical treatment of the infected people, she indicated that some have "greater cardiopulmonary complications than others, but progress favourably," she stated.

Jujuy has registered cases of hantavirus [infections] since 1996, with a yearly average of 17, which generally appear in the summer season. In 2018 there were 7 cases with no fatalities.

Taking these data into account, so far in 2019 there are now 57% more cases compared to last year [2018].

"The majority of the cases are registered until the month of April and we hope that they are maintained within [numbers] expected for this year [2019]," she said, and recalling that more than 20 years ago the cases, "were much higher."

The confirmed [patients] this season were [infected] in the cities of San Pedro, Libertador General San Martin, Calilegua, and in the localities of Aguas Calientes, Palma Sola, and El Remate. Hantaviruses cause an acute virus disease. Wild mice (mainly the long-tailed] mouse) transmit [the virus] to people, and shed the virus in saliva, faeces, and urine.

The most frequent route of infection is by inhalation and occurs when breathing in open or closed places (sheds, gardens, pastures), where faeces or urine of infected rodents shed the virus, contaminating the environment. Other ways to contract the disease are by direct contact, that is to say, touching live or dead infected rodents or the urine or faeces of these rodents and person to person when there is close contact with an infected person during the 1st symptomatic days, through aerosols.

The symptoms of hantavirus [infections] are flu-like: fever, muscle pain, chills, headache, nausea, vomiting, abdominal pain, and diarrhoea. After a few days, respiratory difficulty may appear and get worse.
======================
[The hantaviruses responsible for these 11 cases are not stated in the report above. An earlier report from Jujuy province this year (2019) apparently presumed that the hantavirus involved in that case was Laguna Negra, although it is not stated that this virus had been laboratory confirmed. As noted in ProMED-mail archive no. http://promedmail.org/post/20110430.1348, several hantaviruses have been associated with human infection and hantavirus pulmonary syndrome in Argentina: Andes virus (western Argentina, in the long-tailed pygmy rice rat host, _Oligoryzomys longicaudatus_); related Andes-like viruses Hu39694 (in central Argentina; rodent host unknown); Lechiguana (in central Argentina in the yellow pygmy rice rat, _O. flavescens_); Oran (in northwestern Argentina in _O. longicaudatus_); Bermejo (western Argentina in _O. flavescens_); and Laguna Negra (in northern Argentina in _Calomys laucha_). Without laboratory confirmation, it is not possible to say with certainty which hantavirus was involved. Andes virus seems unlikely in this case. - ProMED Mod.TY]

[Maps of Argentina:
<https://www.ezilon.com/maps/south-america/argentina-maps.html> and
<http://healthmap.org/promed/p/53166>]
22 Mar 2019
Argentina (Santa Fe province and national).

(Conf.) 180 cases. Municipality most affected: Santa Fe 105 cases. Nationally, the localities with dengue cases are: Ingeniero Juarez (Formosa province), Puerto Iguazu (Misiones), Los Blancos, Oran, and Tartagal (in Salta); Santa Fe, Rosario and Buenos Aires cities; the partido La Matanza and the department of Ledesma in Jujuy. DEN-1 virus circulating with 2 patients with DENV-4. 36 cases with history of travel to Brazil, Bolivia, Colombia and Dominican Republic.

<https://www.ellitoral.com/index.php/id_um/192748-brote-de-dengue-ya-es-uno-de-los-mas-importantes-en-la-historia-de-la-ciudad-en-la-provincia-confirman-180-casos-area-metropolitana.html> [in Spanish]
Date: Mon 28 Jan 2019 19:10 ART
Source: Tiempo Sur [in Spanish trans. ProMED Mod.TY, edited]
<https://www.tiemposur.com.ar/nota/165198-hay-31-casos-confirmados-por-el-brote-de-epuyen>

There are now a total of 31 confirmed cases of hantavirus [infections] in the Epuyen [Chubut province] outbreak. The positive cases during recent weeks were under observation and isolation. The numbers of cases of people under observation are reduced to 89.

The Chubut [province] Ministry of Health confirmed in its most recent official statement that there are now 31 confirmed cases of hantavirus [infections], while there are others who are currently under observation. The details of the information provided by the provincial health office explained that on [Fri 25 Jan 2019] an adult patient who had been convalescent from this disease was released from the Esquel Zone Hospital. Also, the same statement mentioned that a hantavirus infection positive patient was released from the intensive care unit in the same hospital and is convalescing in a ward in that hospital.

As an additional comment, the Ministry of Health also remarked the same [Fri 25 Jan 2019] that an adult patient, resident of the El Maiten locality [Chubut province] who was maintained under strict, supervised isolation at home, was later sent to the Esquel Zone Hospital and was confirmed positive for this disease, bringing to 31 the number of confirmed cases.

In the same statement, it was explained that during Friday afternoon [25 Jan 2019] there was notification of the admission of a patient under observation in the Sub Zonal Hospital in El Maiten and is currently under strict isolation.

In that respect, it also is worth clarifying that the measure of selective respiratory isolation effectively accomplished at home is continued, a measure pushed by the same Chubut Ministry of Health, that has reached 89 people.

Coordinated tasks
-----------------
Within the guidelines set by the Ministry of Health of Chubut, the Under secretariat of Human Rights, under the Ministry of Government, coordinated a working day at the local Epuyen Cultural Center, where the different emerging issues of the health contingency affecting the locality were addressed. The proposal arose from attitudes and behaviours that show negative beliefs, as well as forms of stigma and discriminatory practices in the community that transcend the theme of health and have an impact on the lives of the people.
======================
[The number of confirmed cases of hantavirus infection continues to increase. The last ProMED-mail post on 19 Jan 2019 (Hantavirus - Americas (06): Argentina (4 provinces) http://promedmail.org/post/20190123.6274142), reported that since the beginning of the epidemiological contingency (on 3 Dec 2018) in that province, there were 29 confirmed cases (27 in Esquel, one in Bariloche, and another in Chile), of which 11 died. The total case count given above is now 31. The current total of deaths is not mentioned in the report above. Except for the index case, the transmission that followed is presumed to be interpersonal and is the reason for isolation of potential contacts. As mentioned in the previous ProMED-mail post, interpersonal transmission of the current Andes hantavirus outbreak in Chubut is unusual. However, person to person transmission has happened before. Mod.PMB provided a reference that indicates that in 1996 there was an outbreak of Andes virus Epilink/96 variant in El Bolson, Rio Negro province, and that starting with the index case, a molecular analysis indicated that 15 cases occurred subsequently. Of these 16 patients, 9 died. Of the total cases, 8 probably became infected in a hospital environment, including 5 physicians (3 died) and a receptionist in a private clinic where 4 more cases occurred. The receptionist died. The data in this study suggest the possible existence of 3- and 4-person transmission chains, assuming that only one rodent-to-human transmission event occurred. It is prudent to see that the relevant agencies working in the area are addressing the social dimensions of this outbreak. There is a small population in this locality and it is easy to understand how this outbreak has sparked rumors and false information that can lead to socially adverse opinions, attitudes, and behaviors.

Reference
---------
Padula PJ, Edelstein A, Miguel SD, et al. Hantavirus pulmonary syndrome outbreak in Argentina: molecular evidence for person-to-person transmission of Andes virus. Virology. 1998; 241(2): 323-30;  <https://www.sciencedirect.com/science/article/pii/S0042682297989765?via%3Dihub>.

An additional study described 4 clusters of cases in Argentina with probable interpersonal transmission: the 1st a father to son, the 2nd in a rural family, the 3rd among 4 friends who shared a rural cabin, and the 4th a person in contact with another person who, in turn contacted a further person.

Reference
---------
Martinez VP, Bellomo C, San Juan J, et al. Person-to-person transmission of Andes virus. Emerg Infect Dis. 2005; 11(12): 1848-53;
<https://wwwnc.cdc.gov/eid/article/11/12/05-0501_article>.

It is clear that interpersonal Andes hantavirus transmission occurs, although infrequently, more often than ProMED-mail has reported. - ProMed Mod.TY

[Maps of Argentina:
<https://www.ezilon.com/maps/south-america/argentina-maps.html> and
<http://healthmap.org/promed/p/21365>]
Date: Thu 17 Jan 2019
Source: Express [edited]
<https://www.express.co.uk/news/world/1073844/argentina-Hantavirus-outbreak-symptoms-Entre-R-os-Adolfo-Rubinstein-rodents-rats>

Argentina is on lockdown after a deadly virus typically found in rodents has spread to humans, killing 12. A dozen deaths have already been confirmed following a horrific outbreak of the so-called hantavirus, a dangerous disease that affects the pulmonary system after patients become infected through the faeces and urine of rats. Horrifying symptoms, which come on in stages and begin with a fever before ending with haemorrhaging organs, spread at a frighteningly fast rate. The 1st death was a 25-year-old man on Wednesday morning [16 Jan 2019], and another 11 had been announced in just 24 hours. The outbreak happened in the northeast Argentine province of Entre Rios, medical sources have confirmed. Health officials are in the process of battling to control the illness.

The Secretary of Health of Argentina, Adolfo Rubinstein, said in a local radio interview: "Fundamentally, up to now, the route of contagion was the sporadic cases by inhalation of mice secretions. The difference is that it is interhuman contagion; this is what is much more worrisome from the epidemiological point of view."

He also said that the government suspects the Hantavirus outbreak is a "mutation" since "interhuman contagion" can occur.  He stressed that the patients go through a "very serious condition" since this outbreak is registering a "very high mortality, of more than 40%."  He also said the chain of symptoms in humans began when a couple shared a table at a restaurant, which triggered the virus after germs were transited between the pair.

The disease is transmitted by contact with urine, saliva, and droppings of rodents infected with the virus. For transmission between people, a close contact must be made with the patients in the initial period of the febrile episode, which goes from the first 48-72 hours.  The route of propagation is inhalation, so kisses and hugs can get people infected, as well as the saliva particles when speaking. Other symptoms include muscular pains, chills, headaches, nausea, or diarrhoea.

The deer mouse, the white-footed mouse, the rice rat, and the cotton rat are the only types of rodents capable of passing the virus onto humans, with the breeds prominent in Argentina and other areas of South America. [This is incorrect. None of these species occur in Argentina. The deer mouse (_Peromyscus maniiculatus_) and the white-footed mouse (_P. leucopus_) are distributed from Canada to Mexico. The rice rats, several species in the genus _Oryzomys_, and cotton rats, several species in the genus _Sigmodon_, occur from the USA to northern South America. Several other species are hosts of various hantaviruses in Argentina that can infect humans (see the list in the comment above). - ProMED Mod.TY].  [Byline: Carly Read]
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[There have been a few sporadic cases of hantavirus infection in Entre Rios province in the past. In 2011, there were 4 confirmed cases of hantavirus pulmonary syndrome in the province, 2 of which died (see ProMED-mail Hantavirus update 2011 - Americas (26): Chile, Argentina, USA http://promedmail.org/post/20110523.1562). In 2013, there was a single case there. The specific hantaviruses involved in these cases, including the current ones above, are not specified. This report states that the 12 cases were confirmed, but the specific hantavirus involved is not mentioned, nor if the confirmation was made on clinical grounds or by laboratory test (and if so, which test). The unusual human-to-human transmission raises several questions that are discussed below for this Entre Rios outbreak and for the one in Chubut province. - ProMED Mod.TY]
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