Date: Thu 27 Sep 2018
Source: Bio Bio Chile [in Spanish, machine trans., edited]
<https://www.biobiochile.cl/noticias/nacional/region-del-bio-bio/2018/09/27/explosivo-incremento-casos-de-hepatitis-a-aumentan-un-140-en-regiones-del-bio-bio-y-nuble.shtml>

A 140% increase has occurred in 2018 in cases of hepatitis A, in the area that includes the regions of Bio Bio and Nuble, compared to the same date of 2017. In fact, in 2018, 779 cases have been reported, worrying figures for the authorities due to the increase registered since the start of the outbreak of the disease in 2013. According to the health secretary in Bio Bio, Erick Jimenez, the causes could be associated with the consumption of non-potable water, incorrect handwashing, and lack of adequate cooking of seafood.

The communes most affected by hepatitis A are Coronel, where 122 cases were reported, followed by Talcahuano with 94 and Concepción with 78. Despite the figures recorded in the commune of Cuenca del Carbón, epidemiologist Andrea Silva indicated that there will be no focused work in that commune. As of 9 Sep 2018, a total of 11 940 infants in the area had been vaccinated against hepatitis A. [byline: Nicolas Parra]
======================
[The cases are not broken down in regards to age. In children, most cases of HAV infection are subclinical so it is likely that the cases reported were in adults. In the developing world, HAV is not reported much in adults as most children have been infected, and therefore immune to subsequent infection, by the age of 10. That outbreaks are occurring in the area suggests improvement in potable water so less children are infected and therefore still susceptible to HAV as adults. - ProMED Mod.LL]

[Maps of Chile: <https://tinyurl.com/yaklcu2s>
and <http://healthmap.org/promed/p/7>.]
Date: Fri 21 Sep 2018
Source: Biobiochile [machine trans., edited]
<https://www.biobiochile.cl/noticias/nacional/chile/2018/09/21/brote-de-colera-alcanza-los-31-casos-en-tres-regiones-del-pais.shtml>

The Ministry of Health confirmed that from June 2018 to date, 31 people have been infected with cholera in 3 different regions of the country. The microorganism has been present in Chile for some time, but the Undersecretary of Public Health, Paula Daza, told El Mercurio that "this year [2018] what we have had is an outbreak, because we've had a larger number of cases in a short period of time."

According to data from the Regional Ministerial Secretariat (Seremi) of Health of the [Santiago] Metropolitan Region, of the total number of patients, 29 are in this region, with the municipality of La Florida leading the list with 4 infections. Other communes with reported cases are Huechuraba, Las Condes, Vitacura, La Reina, Penalolen, Puente Alto, La Cisterna, Pedro Aguirre Cerda, Santiago, Maipu, Central Station, Renca, Quinta Normal, Conchali, Independencia, Recoleta, and Providencia.

The list is magnified by other cases that occurred in the regions of Valparaiso and Atacama. Of the total number of patients registered so far, 19 are women, and 18 had a history of other underlying diseases.

The symptoms of the infection are similar to a prominent gastroenteritis. The Ministry of Health confirmed that currently no deaths have been recorded as a result of the infections, but 9 people had to be hospitalized.

As to which polluted irrigated waters were the trigger of the outbreak, the Health Seremi of the Metropolitan Region, Rosa Oyarce, assured the same media that "it was ruled out because all the necessary tests were done to the irrigation canals that go directly to the irrigations of the vegetables." Meanwhile, Deputy Secretary Paula Daza indicated that the cause of the outbreak cannot yet be determined. The health authority stressed that it has been ruled out that the bacterium came from abroad, because the ministry's information indicates that none of the patients took previous trips to other countries that could have caused the infection.  [Byline: Felipe Diaz]
===============================
[In the previous post, 14 cases were reported; now that number has more than doubled. Chile had a toxigenic cholera outbreak that originated in neighboring Peru between 1991 and 1994, affecting approximately 150 persons.

It is not stated if this cluster of cases is related to a non-toxigenic O1 or O139 strain or a non-epidemic strain of non-O1, non-O139 _Vibrio cholerae_. As a review, the flagellar (H) antigens of _V. cholerae_ are shared with many water vibrios and therefore are of no use in distinguishing strains causing epidemic cholera. The O (somatic) antigens, however, do distinguish strains of _V. cholerae_ into 139 known serogroups. Almost all of these strains of _V. cholerae_ are non-virulent. Until the emergence of the Bengal (O139) strain (which is "non-O1"), a single serogroup, designated O1, has been responsible for epidemic cholera.

There are 3 distinct O1 serotypes -- Ogawa, Inaba, and Hikojima -- each of which may display the "classical" or El Tor phenotype (or biotype). The biotypes are distinguished by their expression of surface antigens A, B, and C. Ogawa contains antigens A and B; Inaba contains antigens A and C; and Hikojima contains antigens A, B, and C. The latter serotype is relatively rare.

In almost all cases, non-O1, non-O139 _V. cholerae_ isolates do not possess the genes for cholera toxin. Some isolates can cause substantial diarrhea (1-4). The type III secretion system (TTSS) is a mechanism for Gram-negative bacilli to introduce effector proteins into host cell cytoplasm (5). It has been reported that a functional TTSS is required for at least in some non-O1, non-O139 isolates to induce diarrhea in an animal model associated with small-bowel damage and production of proinflammatory cytokines (6). In addition, TTSS contributes to virulence even in the presence of cholera toxin and TCP (6).

References
----------
1. Bhattacharya MK, Dutta D, Bhattacharya SK, et al. Association of disease approximating cholera caused by _Vibrio cholerae_ of serogroups other than O1 and O139. Epidemiol Infect. 1998; 120(1): 1-5; <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2809342/>.
2. Sharma C, Thungapathra M, Ghosh A, et al. Molecular analysis of non-O1, non-O139 _Vibrio cholerae_ associated with an unusual upsurge in the incidence of cholera-like disease in Calcutta, India. J Clin Microbiol. 1998; 36: 756-63;  <http://jcm.asm.org/content/36/3/756.long>.
3. Bidinost C, Saka HA, Aliendro O, et al. Virulence factors of non-O1, non-O139 _Vibrio cholerae_ in Cordoba, Argentina. Rev Argent Microbiol. 2004; 36: 158-63;  <https://www.ncbi.nlm.nih.gov/pubmed/15786867>.
4. Chatterjee SC, Ghosh K, Raychoudhuri A, et al. Incidence, virulence factors, and clonality among clinical strains of non-O1, non-O139 _Vibrio cholerae_ isolates from hospitalized diarrheal patients in Kolkata, India. J Clin Microbiol. 2009; 47(4): 1087-95; <http://jcm.asm.org/content/47/4/1087.long>.
5. Gatan JE, Colimer A. Type III secretion machines: bacterial devices for protein delivery into host cells. Science 1999: 284(5418): 1322-8; <http://science.sciencemag.org/content/284/5418/1322.long>.
6. Shin OS, Tam VC, Suzuki M, et al. Type III secretion is essential for the rapidly fatal diarrheal disease caused by non-O1, non-O139 _Vibrio cholerae_. mBio 2011; 2(3): e00106-11; <http://mbio.asm.org/content/2/3/e00106-11.long>.
- ProMed Mod.LL]

[HealthMap/ProMED-mail map:
Chile: <http://healthmap.org/promed/p/7>]
Date: Wed 5 Sep 2018
Source: El Comercio [in Spanish, machine trans. edited]
<https://elcomercio.pe/mundo/latinoamerica/chile-brote-hepatitis-suma-201-casos-region-antofagasta-noticia-nndc-554166>

Health authorities in the region of Antofagasta in northern Chile are on alert for an outbreak of hepatitis A that adds 201 cases so far in 2018, 2 more than those recorded throughout 2017, they said today, 5 Sep 2018. "Unfortunately, we are having about 5 cases every 2 weeks, which means that we are facing an epidemic," Cooperativa Rossana Díaz, ministerial regional Secretary of Health, told Radio. It is a situation "that is controllable with the help of the community," which, in his opinion, has a fundamental role in the prevention of this disease, which can "be fulminating, create a risk to life, and require organ transplantation." Diaz stressed that hepatitis A can be prevented with simple measures, such as constant hand washing and optimal handling and preparation of food.

The authorities must combat street food sales and control businesses, "but we do not get anything if people continue to consume food on the street or in places that do not have sanitary authorization for that," he said. The profusion of cases, according to the official, corresponds to the increase in the consumption of food in unauthorized places and the lack of vaccinated personnel or strict hygiene regulations in establishments that do have a permit.

The authorities have set up an Outbreak Response Committee in the region and questioned contacts of the confirmed cases and of the suspects in order to find the origin of transmission. The cases registered in Antofagasta range from 2 to 60 years, with an average of 23 years, of which 62% are men and 38% are women, and although the presence of immigrants is large in the region, 98% of the cases are Chileans, the regional authorities reported.

Hepatitis A, according to the Institute of Public Health, can be prevented with a vaccine, and its detection requires a medical diagnosis in addition to laboratory tests or diagnostic imaging studies. It is transmitted through water, contaminated food, or through contact with an infected person. It is considered a disease with worldwide distribution that occurs sporadically or epidemically with a seasonal cycle, which in Chile is an intermediate endemic, with epidemic outbreaks every 4 or 5 years, and there are no chronic carriers.
==============================
[It seems to be the case that the cases are occurring at a low, steady rate rather than from a specific recent exposure.

Antofagasta (<https://en.wikipedia.org/wiki/Antofagasta>) is a port city in northern Chile, about 1100 km (700 mile) north of Santiago. It is the capital of Antofagasta province and the Antofagasta region. Formerly part of Bolivia, Antofagasta was captured by Chile in the War of the Pacific (1879-83), and the transfer of sovereignty was finalized in the 1904 Treaty of Peace and Friendship between the 2 countries. - ProMED Mod.LL]

[HealthMap/ProMED map available at: Antofagasta, Antofagasta, Chile:
<http://healthmap.org/promed/p/11048>]
Date: Tue, 31 Jul 2018 05:26:55 +0200
By Ana FERNANDEZ

Atacama, Chile, July 31, 2018 (AFP) - Open air rock paintings in the world's driest desert pay testament to the importance of the llama to millennia-old cultures that traversed the inhospitable terrain.   Conservationists working in Chile's Atacama Desert want UNESCO to recognize the Taira Valley drawings as a heritage site so they can develop sustainable tourism in the region.

Taira is "a celebration of life," said archeologist Jose Bereguer, describing the site as "the most complex in South America" because of its astronomical importance as well as the significance to local shepherds.   The rock art was a "shepherd's rite" needed to ask the "deities that governed the skies and the earth" to increase their llama flocks.   First rediscovered by Swedish archeologist Stig Ryden in 1944, the Taira rock art is between 2,400 and 2,800 years old.   It is made up of a gallery of 16 paintings more than 3,000 meters (9,842 feet) above sea level on the banks of the Loa River that traverses the desert.

The jewel in the crown are the Alero Taira drawings some 30 meters from the Loa in a natural shelter, in which the importance of the llama becomes abundantly clear.   Not just the principal source of wealth for desert dwellers over thousands of years, the llama has been used in ritual ceremonies throughout the Andes for just as long, such as in the "Wilancha," or sacrifice to "Pacha Mama," or Mother Earth.

- 'Possible to delve' -
"No one can understand the things done 18,000 years ago because the cultures that did them have disappeared," said Berenguer, curator at Santiago's Museum of Pre-Columbian Art.   "Here, it's possible to delve into the meaning because we have ethnography and because there are still people living in practically the same way as in the past."

According to Rumualda Galleguillos, one of around 15 indigenous people still raising llamas in the Atacama Desert like their ancestors, these pictures are a "testament" to forefathers who could neither read nor write.   Around 90 precent of the engravings, painted mainly in red but also ochre yellow and white, depict llamas of various sizes, some pregnant, others suckling their young.   But the remaining 10 percent depict the desert's diversity, such as foxes, snakes, ostriches, partridges and dogs.

The few human figures that appear are tiny, as if those painting them "wanted to go unnoticed in front of the greatness of animals that were so important to their economy," said Berenguer.   What the paintings also demonstrate is that 2,500 years ago, people were already studying the stars in an area that has more recently become the astronomy capital of the world with some of the most powerful telescopes ever built.   A book written in conjunction with the Atacama observatory called "The Universe of our Grandparents," claims that the ancient inhabitants of this area studied the stars to help learn how to domesticate the inhospitable desert and survive its dangers.

- Seeing llamas -
In this vision, the universe is made up of the skies and Earth as one whole, with the skies forming the horizon of life. What is seen in the skies is a reflection of what there is on Earth.   Unlike the Greeks, though, ancient Atacama astrologists didn't see Orion, Gemini or Cancer.

They saw llamas, their eyes, corrals, a loaded slingshot and a shepherd standing with his legs spread wide and arms in the air, worrying about foxes, said Silvia Lisoni, a professor of history and amateur astronomer.   Taira is located on an axis that aligns the sacred Sirawe "sandy eye" quicksand from where locals would pray for rain, the San Pedro volcano, the Colorado hill, and the Cuestecilla pampas, another sacred spot.

Volcanoes, like springs, were considered deities by the Atacama natives, while llamas were thought to have been born of springs.   The Alero Taira is positioned so that it is completely illuminated by the sun on both the winter and summer solstices.   "There's evidence that this site was built here for specific reasons," said Berenguer.

Taira is not the oldest example of rock art in this part of Chile, though. To the north in the copper mining Antofagasta region lies Kalina, around 1,000-1,200 years older than Taira, and Milla.   This style of art has been found also in the Puna de Atacama plateau in neighbouring Argentina, but Taira "has few equals in terms of beauty and complexity," said Berenguer.   One day, he hopes that Taira will be afforded UNESCO World Heritage Site status like the rock art in the Cave of Altamira in Spain or France's Lascaux caves.
Date: Mon, 30 Jul 2018 03:58:38 +0200
By Paulina ABRAMOVICH

Santiago, July 30, 2018 (AFP) - Easter Island is known for its unique Moai monumental statues carved by the Rapa Nui people, believed to have arrived on the remote landmass in the southeastern Pacific Ocean in around the 12th century.

Despite its isolated location some 3,500 kilometers (2,000 miles) from the coast of Chile, the island is a popular tourist destination, not least due to its remarkable collection of around 900 tall human figures with distinctive features and standing up to 10 meters (32 feet) tall.   However, it is those very tourists, alongside mainland migrants, who have become a threat to the island's well-being. Chile, which annexed the territory in 1888, has decided to act.

In 2007, Easter Island was designated a special territory while back in March, congress voted to limit the number of tourists and foreign or mainland residents allowed on the island, and the time they're allowed to stay.   As of Wednesday, new rules will come into effect that reduce the time tourists -- Chileans not part of the Rapa Nui people and foreigners -- can stay on the island from 90 to 30 days.   "Foreigners are already taking over the island," Mayor Pedro Edmunds told AFP.

At the last census in 2017, there were 7,750 people living on Easter Island, almost double the population of a few decades ago, before the island was hit by a tourism boom and the real estate development that accompanied it.   Edmunds says that number is 3,000 "too many."   "They're damaging the local idiosyncrasy, the thousand-year culture is changing and not for the good," he added, saying that "customs from the continent" were infiltrating the island and "that's not positive."

Crime and domestic violence figures are also rising.   It's not just obnoxious people from the mainland causing problems, though -- the increase in tourism is harming the environment.   All basic services are straining under the pressure, not least waste management, Ana Maria Gutierrez, the local government's environmental adviser told AFP.   A decade ago the island generated 1.4 metric tons (1.5 US tons) of waste per year per inhabitant, but that figure has almost doubled to 2.5 tons today, with a population that recycles very little.   "Environmentally the island is very fragile," said Gutierrez.

The new laws, however, impose stricter rules on those who wish to live on the island, amongst them a requirement to be related to someone from the Rapa Nui people: either a parent, partner or child.   Others who will be allowed to stay are public servants, employees of organizations that provide services to the government, and those who develop an independent economic activity alongside their families.   On arrival, tourists must present their hotel reservation or an invitation from a resident.   The rules will also establish a yet-to-be-decided maximum capacity.

But Edmunds isn't happy, as he feels the rules don't go far enough to protect the island's culture, heritage and singularity.   "I don't agree with these rules, it's not enough because it doesn't reflect all the aspirations of the island," he said, admitting that like "many other Rapa Nui" he favors a "total" ban on the arrival of new residents.   However, he said the legislation was at least "a good start."   Rapa Nui are a Polynesian people closely related to those on Tahiti, whereas the majority of Chileans have European ancestry, with a minority of indigenous peoples.
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