Date: Tue 30 Jul 2019
Source: Food Safety News [edited]
The public health institute in Germany has reported more than 30 people have been sick with _E. coli_ in 2019 after going to Egypt. The Robert Koch Institute (RKI) noted increased reports of enterohemorrhagic _E. coli_ (EHEC) related to or after staying in Egypt. Earlier in July 2019, Public Health England (PHE) also reported an increase in adults and children ill after coming back from Hurghada in Egypt.
In Germany, there are 31 cases of EHEC and 5 people with haemolytic uremic syndrome (HUS), a type of kidney failure associated with this form of _E. coli_ infection. This is significantly more than in the same period of previous years. In 2018, there were 21 EHEC and one HUS case. In 2017, 9 EHEC and 1 HUS case were recorded. The rise cannot be explained by the increase in travel to Egypt alone, according to RKI.
It follows a warning by PHE after 18 people fell ill with EHEC infection and one person developed HUS after returning from Egypt in 2019. 4 people needed hospital treatment. A PHE spokeswoman previously told Food Safety News that it was not a single outbreak as a variety of different EHEC strains had been detected in visitors to Egypt with EHEC O157 and EHEC O26 among them. The agency has told the European Centre for Disease Prevention and Control (ECDC) about the cases.
What caused the German cases is unknown and sick people have stayed at different hotels in separate places, according to RKI, which has informed Egyptian authorities about the increase.
Dr Nick Phin, deputy director of the National Infection Service at PHE, said there are precautions that travellers can take. "These include ensuring meat is cooked thoroughly, not drinking tap water or ice made from tap water and trying to avoid swallowing water when swimming. Anyone suffering from diarrhoea and vomiting should ensure they keep well hydrated and seek medical advice if their symptoms don't improve within 48 hours. They should also avoid preparing or serving food while they have symptoms and thoroughly wash their hands after using the toilet to stop the bug being passed to others" he said. [Byline: Joe Whitworth]
[This is the 2nd European country to report a spike to travel-related cases of EHEC related to Egypt. The German report does not specifically relate the cases to the Red Sea area of the country.
As a review, the classical enterohaemorrhagic _E. coli_ is the O157:H7 serotype although some are non-motile, that is, H-. Most O157 strains do not ferment sorbitol and that characteristic was used to screen for the strain using a sorbitol MacConkey agar. However, since non-O157 EHEC strains such as O26, O45, O103, O111, O121, and O145 do ferment sorbitol and, as seen here, some O157 also ferment sorbitol, laboratories now look for these isolates using genetic assays for the Shiga toxin genes.
Around 1903 Smith and Reagh reported on the different behaviour of salmonella strains. Their work was mostly ignored until Weil and Felix, working on _Proteus_ cultures, noted 2 forms, the swarming form called the H form (_mit Hauch_, in English: "with breath") and the non-swarming form, called the O form (_ohne Hauch_, in English: "without breath"). The H form contained both O and H antigens (correctly termed the OH form). These parallels were transposed to other Enterobacteriaceae.
If O antiserum is added to a culture, motility is preserved, whereas if H antiserum is added the culture does not move. Therefore, H antigen was involved with swarming in the agar plate (breathing might have been used to imply the ability to move). (_E. coli_, of course, do not swarm on certain agar plates like _Proteus_ bacteria do). - ProMED Mod.LL]