Date: Tue 23 Oct 2018
Source: The Bush Chicken [edited]
<http://www.bushchicken.com/seven-cases-confirmed-in-grand-gedeh-measles-outbreak/>

The director for immunization at the Ministry of Health says there are currently 29 reported measles cases in Grand Gedeh, with 7 of those cases confirmed.

Director for immunization at the Health Ministry Adolphus T. Clarke said reports of the outbreak in Tchien district 1st emerged on [Wed 17 Oct 2018]. Speaking to The Bush Chicken in an exclusive interview, Clarke said out of the 29 cases reported, health officials in the area realized that 11 children under 5 years of age were affected by the disease. The other children were older than 5.

"The 29 cases identified were managed at the Martha Tubman Memorial Hospital in Zwedru, and the affected children fully recovered with no death reported."

With support from the Ministry of Health, Clarke said the county responded quickly with vaccinations. "The exercise has concluded, and health officials were able to reach a total of 1551 children not less than 5 years," he said. "So I can say that the county responded swiftly to the outbreak of the disease and recorded zero deaths."

However, things did not go smoothly. Due to the poor road conditions in the south-eastern region, Clarke said some health officials who left Monrovia with vaccinations for Grand Gedeh endured difficulties during the journey. "Others had to travel through neighbouring Ivory Coast to reach the country," he said.

The director indicated that, due to the challenge in attaining high vaccination coverage, health authorities in the country knew that, at some point in time, there would be sporadic outbreaks of the disease in the county.

Clarke said the current outbreak was not severe, because the ministry has dealt with sporadic outbreaks of measles in the past. He noted that health officials in Grand Gedeh have now been encouraged to carry out vaccination campaigns in affected and nearby communities as the dry season approaches.

"We have encouraged mothers to make use of the health facilities in the county and ensure that their children are vaccinated against all the diseases the ministry is preventing," Clarke said.  [Byline: Zeze Ballah]
Date: Thu 27 Sep 2018
Source: Front Page Africa [edited]
<https://frontpageafricaonline.com/health/liberia-yellow-fever-suspected-in-grand-kru-county/>

The National Public Health Institute of Liberia (NPHIL) in collaboration with the Ministry of Health (MoH) and partners is investigating a suspected case of yellow fever in Grand Kru County.

According to a release issued in Monrovia, the suspected case is a 2-year-old female from Farina Town, Barclayville Health District. There has been no death or new cases reported. The suspected case has been managed and is in good health.

A blood specimen has been collected and sent to the National Public Health Reference Laboratory (NPHRL) for confirmation. According to the release, health authorities in the county are conducting an active case search, risk assessment, and planning for a possible reactive vaccination exercise, pending the laboratory result.

Since January 2018, this is the 2nd reported suspected case from Grand Kru County. The 1st was a 29-year-old female from Dorbor District.

There have been no confirmed cases of yellow fever in the country since the 2009 nationwide preventive vaccination campaign. The release also noted that a total of 94 suspected cases of yellow fever have been recorded across the country since the beginning of 2018.

Yellow fever is an acute viral haemorrhagic disease transmitted by infected mosquitoes. The symptoms include fever, headache, jaundice, muscle pain, nausea, vomiting, and fatigue. Communities have been advised to report unexplained deaths for safe and dignified burials as measures to prevent infection. Community engagement and response activities have been intensified in the area.

Meanwhile, the public is advised to take the following public-health measures:
- Keep your environment clean
- Visit a health facility immediately when you feel the symptoms of yellow fever
- Continue sleeping under treated bed nets

Yellow fever is not transmitted through body touch or body fluids.
=====================
[Yellow fever (YF) cases have occurred sporadically in Liberia, although the last YF ProMED-mail post was in 2009. The 94 suspected YF cases this year (2018), including the most recent one above, is a cause for serious concern. It is important to have a timely laboratory diagnosis and well-developed contingency plans should YF be confirmed. YF can quickly spread if a significant proportion of the human population is unvaccinated and the vector mosquitoes are abundant. The above report does not indicate the number of unvaccinated individuals nor the status of the vector mosquito population. - ProMED Mod.TY]

[HealthMap/ProMED-mail map:
Grand Kru County, Liberia: <http://healthmap.org/promed/p/32407>]
Date: Fri 6 Jul 2018, 5:00 PM
Source: WHO Weekly Bulletin on Outbreaks and Other Emergencies [edited]
<http://apps.who.int/iris/bitstream/handle/10665/273028/OEW27-300606072018.pdf?sequence=1&isAllowed=y>

Event Description
-----------------
Liberia has continued to experience sporadic cases of Lassa fever since the beginning of 2018. In week 25 (week ending 26 Jun 2018), 2 new confirmed Lassa fever cases were reported in Nimba County, the only county with active transmission currently. Nimba County has reported 5 confirmed Lassa fever cases since [12 May 2018]. In the latest event (the 2 confirmed cases in week 25), the 1st case-patient, a 59-year- old male from Gbehlay Geh district, fell ill on [4 Jun 2018] and was treated with antimalarials and antibiotics at a local clinic. On [20 Jun 2018], the case-patient presented to a public hospital with fever and other constitutional symptoms, and had bleeding from a venepuncture site.

On [21 Jun 2018], a blood specimen was collected and sent to the National Public Health Reference Laboratory (NPHRL). The test result released on [26 Jun 2018] was positive for Lassa fever virus infection. The 2nd case-patient, a 41-year-old female, is the wife of the first case-patient (described above). She developed illness on [17 Jun 2018] and was admitted to the same hospital on [20 June 2018] with fever and other constitutional symptoms. Being a known contact, a blood specimen was collected on [21 Jun 2018] and the test result released on [26 Jun 2018] was positive for Lassa fever. The 2 case-patients are admitted under barrier nursing and ribavirin treatment initiated. A total of 26 contacts, including 13 health workers, have been line listed and are being followed up.

Between [1 Jan 2018] and [27 Jun 2018], a total of 130 suspected Lassa fever cases, including 33 deaths, were reported. Of these, 20 cases were laboratory confirmed, 103 were discarded (after testing negative), and 7 cases were not tested due to inadequate specimens. Of the 20 confirmed cases, 14 have died, giving a case fatality rate of 70 percent. Females make up 60 percent (12) of the confirmed cases. The age range for the confirmed cases is 1 to 65 years old, with a median of 32.5 years. The confirmed cases are from 5 counties, namely (Nimba (9), Bong (4), Montserrado (3), Margibi (2), and Grand Bassa (2).

Public Health Actions
---------------------
- The Ministry of Health and the National Public Health Institute of Liberia (NPHIL) are coordinating response activities to the Lassa fever outbreak, with support from WHO, CDC and other partners. The national epidemic preparedness and response committee (NEPRC), under the leadership of NPHIL, have been meeting weekly to review the Lassa fever outbreak situation and provide technical support to sub-national level, with technical support from WHO, and US-CDC; 15 WHO field offices are providing technical and operational support to the response.
- Active surveillance, including case search, case investigation and contact tracing are ongoing in the affected districts. A specimen transport system using couriers is available at designated points across the country to transport specimens to the NPHRL for testing.
- The Ganta United Methodist Hospital has been designated as a treatment centre, and equipped with ribavirin and other medical supplies for case management. Orientation of healthcare workers on case management protocol is ongoing.
- Healthcare workers in the country are being trained on Lassa fever case management and infection prevention and control (IPC) measures by NPHIL and MOH, with support from WHO.
- Health workers' exposure risk assessment is planned to be conducted in the clinic or hospital where the confirmed cases sought care.
- Community engagement activities are ongoing in the affected communities, including home visits and providing information on environmental cleanliness.

Situation Interpretation
------------------------
Sporadic Lassa fever cases continue to occur in certain parts of Liberia where the disease is known to be endemic. Bong, Grand Bassa, Margibi, and Nimba are among the counties that report cases annually. In 2017, a total of 30 confirmed cases were reported from 7 counties. The reason for these sporadic cases is known: the constant interaction of rats (the vector for Lassa fever virus) and people in unsanitary conditions. The national authorities and partners need to prioritize measures mitigating this exposure risk factor by improving vector and environmental management components of the response. This goes along with effective social mobilization and community engagement strategies, targeting vector control and environmental management in the communities. There is also a need to enhance capacity at the subnational levels for early case detection, case investigation, appropriate case management and its associated IPC [infection prevention and control] measures aimed at averting infection among health workers.
========================
[The number of Lassa fever cases in Liberia continues to slowly increase. Between 1 Jan 2018 and 27 Jun 2018, 20 cases were laboratory confirmed, up from 18 cases on 1 Jun 2018. Apparently, all these Lassa fever virus infections were acquired by contact with infected rodents or their excretions. Lassa fever virus can be acquired from infected rodents or patients in the hospital but in the above report, there is no mention of Lassa fever virus nosocomial transmission. Transmission can occur in health facilities when personal protective equipment is not employed and barrier-nursing practices are not adequate to protect staff from blood and secretions of infected patients. The hospitals attending the patients mentioned above do have barrier measures in place.

As mentioned in previous posts, Lassa fever virus transmission to humans occur when people are in contact with the reservoir rodent host, the multimammate mouse (_Mastomys natalensis_ and _M. erythroleucus_) and the African wood mouse (_Hylomycus pamfi_) or their excreta, as was likely the situation in these cases. Rodent control has to be undertaken at the village level with individual households employing the preventive measures listed above. This requires an extensive and continuous public education effort.

Images of the _Mastomys natalensis_ mouse, the rodent reservoir of Lassa fever virus, can be seen at
<https://www.inaturalist.org/taxa/45326-Mastomys-natalensis> and of
_M. erythroleucus_ and _Hylomycus pamfi_ at:
<http://punchng.com/nigerias-large-rat-population-threatens-lassa-fever-war/>. - ProMED Mod.TY]

[Maps of Liberia can be accessed at:
<http://www.theworldmap.net/country/big/liberia/> and
<http://healthmap.org/promed/p/54>]
Date: Fri 15 Jun 2018
Source: WHO Regional Office for Africa, Health Information and Risk Assessment [edited]
<http://apps.who.int/iris/bitstream/handle/10665/272848/OEW24-815062018.pdf>

Weekly bulletin on outbreaks and other emergencies week 24: [11-17 Jun 2018; data as of 15 Jun 2018]
----------------------------------------------------------------------
Liberia: 2930 cases, 14 deaths, 0.5 percent CFR

Event description
-----------------
Liberia has been experiencing recurrent measles outbreaks since the beginning of 2018. In week 23 (week ending 10 Jun 2018), a total of 61 new suspected measles cases (with no deaths) were reported from 13 out of the 15 counties in the country, compared to 72 new cases reported in week 22 [week ending 3 Jun 2018]. 23 blood specimens collected from the suspected cases have been shipped to the National Reference Laboratory, while 20 of the case-patients had epidemiological links to confirmed cases. During the reporting week, 14 out of 92 health districts (in 5 counties) attained measles epidemic threshold of 3 laboratory confirmed cases. The 5 counties are Grand Bassa, Margibi, Maryland, Montserrado, and Nimba.

Between week 1 and week 23 of 2018 [1 Jan-10 Jun 2018], a total of 3086 suspected measles cases were reported. Of these, 177 were laboratory confirmed, 1762 had epidemiological links to confirmed cases, 562 were clinically compatible, 156 were discarded (after testing negative), and test results for 429 cases were pending. Of the 2930 confirmed, epidemiologically linked, clinically compatible, and suspected cases, 14 have died, giving a case fatality rate of 0.5 percent in this group; 558 (19 percent) were vaccinated, 334 (11 percent) were not vaccinated and 2 038 (70 percent) had unknown vaccination status. About 39 percent of the affected people are 4 years of age and below, 25 percent are between 5 and 9 years and 36 percent are 10 years and above.

Public health actions
---------------------
The Ministry of Health Expanded Program on Immunization and the National Public Health Institute of Liberia (NPHIL) are coordinating response activities to the measles outbreak, with support from WHO, UNICEF, and other partners. The national epidemic preparedness and response committee (NEPRC), under the leadership of NPHIL and with technical support from WHO, UNICEF, US-CDC and other agencies, have been meeting weekly to review the measles outbreak situation and provide technical support to sub-national level. WHO has deployed the Polio STOP team in the 15 counties to support sub-national level response.

A nation-wide measles immunization campaign has been conducted across the country in 3 phases since 15 Feb 2018, targeting a total of 654 803 children aged 6-59 months. Preliminary data indicates that 97 percent (63 350) of the targeted populations were vaccinated across the country.

Active search for measles cases continues throughout the country and has been reinforced in districts and communities with sustained outbreaks. Epidemic threshold is monitored weekly across the country through routine data collection and analysis.

All measles cases are being provided with symptomatic management along with a high dose of vitamin A.

The National Public Health Reference Laboratory has been testing samples reported across the country, by serology (IgM detection), and routinely releasing test results.

Communities have been provided with education to seek early care for measles cases at the nearest health facility. Communities have also mobilized through town criers, radio messaging, and posters to ensure high coverage of the immunization campaign among targeted age group.

Situation interpretation
------------------------
Liberia has been experiencing recurrent measles outbreaks since the beginning of the year [2018]. The reason for these outbreaks is known: the accumulation of a large number of susceptible populations over the years due to suboptimal immunization coverage. It is concerning that measles incidence cases are occurring in spite of the 3 phases of mass immunization campaigns conducted since February 2018, with seemingly high administrative coverage. The national authorities and partners need to drastically and speedily reduce the number of susceptible individuals in the most affected age-groups, maintain the build-up of vulnerable individuals at very low levels by immunising a large proportion (over 95 percent) of each new birth cohort and implement additional vaccination activities to periodically protect susceptible individuals who have accumulated.

With the well-developed immunization programme, structures, and systems, such measles outbreaks should be predicted and adequate preparedness measures put in place. Additionally, each measles outbreak should be followed by thorough evaluation of the cause of the outbreak, the surveillance system for early outbreak detection, the preparedness measures preceding the outbreak and the management of the outbreak, and an overall review of immunization programme goals and operations.
==========================
[A map showing the geographical distribution of measles cases in Liberia, week 1-23, 2018 can be seen at the source URL above. - ProMED Sr.Tech.Ed.MJ]

[HealthMap/ProMED-mail map of Liberia:
<http://healthmap.org/promed/p/54>.]
Date: Wed 13 Jun 2018
Source: Daily Observer [edited]
<https://www.liberianobserver.com/news/health-authorities-respond-to-lassa-fever-outbreak/>

The National Public Health Institute of Liberia (NPHIL) in collaboration with the Ministry of Health (MoH) has responded to the Lassa fever outbreak in the country.  According to a release issued in Monrovia, cases of Lassa fever are on the increase in the Lassa belt (Bong, Nimba, and Grand Bassa Counties).

In the country, 4 new confirmed cases have been reported: from Bong (2), Grand Bassa (1) and Nimba (1) since the last outbreak in May 2018. A blood specimen was collected and tested positive for Lassa fever on 4-7 Jun 2018 at the National Public Health Reference Laboratory (NPHRL). The recent case from Nimba County was confirmed by the NPHRL on 7 Jun [2018].

A total of 128 contacts, including 59 healthcare workers, have been line-listed and are being followed up. One case is currently undergoing treatment at Phebe Hospital in Gbarnga Bong County, while one has been discharged; 2 deaths have been reported in this recent outbreak.

Since the beginning of January 2018, a total of 112 suspected cases have been reported across the country, of which 18 have been confirmed positive by RT-PCR (Nimba-7, Montserrado-3, Bong-4, Margibi-2, and Grand Bassa-2. The case fatality rate among confirmed cases is 72.2 percent (13/18). The high death rate is alarming to NPHIL, which has launched an in-depth investigation.

The release also discloses that although Lassa fever is not new to Liberia, it is a deadly viral disease that requires urgent attention. The disease is spread by rodents (rats) through close contact with affected persons [or contaminated environments - ProMED Mod.TY].

People are advised to keep their environment clean: cover dishes to prevent rats from defecating or urinating on them; cover food in tightly closed containers to prevent rats from playing in food or drinking water; do not eat rats because you can get the sickness by coming into contact with their blood, urine or feces, and do not dry food in open places where rats can reach.

Other preventive measures are to avoid body contact with affected persons and endemic zones; visit a health facility immediately when you feel sick.

Meanwhile, NPHIL, MOH, and partners have appealed to the general public to take the necessary preventive measures, and to kindly report cases of fever to the nearest health facility.

"We continue to improve our rapid response at the county, district and community levels through the County Emergency Operation Centers, and to provide technical, financial and logistical support to the outbreaks, the release concluded.
=====================
[The number of confirmed Lassa fever cases in Liberia has increased somewhat since 1 Jun 2018, from 13 to 18 cases.

Lassa fever virus can be acquired from infected rodents or patients in the hospital. In the above report, there is no mention of Lassa fever virus nosocomial transmission. The situation where these people acquired Lassa fever virus is not indicated in these cases.

Virus transmission to humans occurs when people are in contact with the reservoir rodent host, the multimammate mouse (_Mastomys natalensis_ and _M. erythroleucus_) and the African wood mouse (_Hylomycus pamfi_) or their excreta, as was likely the situation in these cases. Rodent control has to be undertaken at the village level with individual households employing the preventive measures listed above. This requires an extensive and continuous public education effort. Transmission can occur in health facilities when personal protective equipment is not employed and barrier-nursing practices are not adequate to protect staff from blood and secretions of infected patients.

Images of the _Mastomys natalensis_ mouse, the rodent reservoir of Lassa fever virus, can be seen at
<https://www.inaturalist.org/taxa/45326-Mastomys-natalensis> and _M. erythroleucus_ and _Hylomycus pamfi_ at:
<http://punchng.com/nigerias-large-rat-population-threatens-lassa-fever-war/>. - ProMED Mod.TY]

[Maps of Liberia can be accessed at:
<http://www.theworldmap.net/country/big/liberia/> and
<http://healthmap.org/promed/p/54>.]
More ...